Discover and read the best of Twitter Threads about #parkinsons

Most recents (10)

On #WorldBrainDay, the Neuronet programme is celebrating @IMI_JU's public-private partnerships in #neurodegeneration research; from fundamental science to clinical studies, data analysis to knowledge mining & beyond.

Keep your eyes peeled! #WeAreNeuronet
2/20 @bwfalcon, now a group leader at @MRC_LMB, worked on the structure of Tau filaments @imprind, showing how they are misfolded in the brains of people with #neurodegenerative diseases.

Read about his work here: bit.ly/IMPRIND-falcon #WorldBrainDay
3/20 #WorldBrainDay 2020 is dedicated to raising awareness of #Parkinsons disease. There are currently no disease-modifying treatments for mild cognitive impairment in PD; the #PD-MIND project aims to test a new drug to treat this condition. Find out more:bit.ly/PD-MIND
Read 21 tweets
Check out the latest preprint from the lab on "Integration of #Genomic & Multi-tissue #proteomic data in neurodegenerative diseases" lead by @chengran2020 @WUSTLdbbs in @ccrugom lab at @WUSTLmed supported by @cziscience via @medrxivpreprint medrxiv.org/content/10.110… #tweetorial ⬇️
This is the first #proteomic study that uses high throughput pQTL in neurological relevant tissues to identify novel genetic loci regulating protein levels, which will improve our understanding of the biology of #Alzheimers, #Parkinsons, & other neurodegenerative diseases
We identified hundreds of novel pQTLs in CSF, plasma, & Brain linking novel genes, biomarkers and drug targets with #Alzheimers, #Parkinsons
Read 10 tweets
NEW: “When does postural instability appear in monogenic parkinsonisms? An individual-patient meta-analysis” in The Journal of Neurology.
A 2-year effort with @LucaMarsili1 @andrea_sturchio @Dr_Murli_Mishra @DrAlfonsoFasano @nachogenePD @Marcelokauffman @AlbertoEspay
THREAD 🧵
LINK: link.springer.com/article/10.100…

Monogenic parkinsonisms are very different from one another. Not only on the severity of parkinsonism, but also on cognition, behavioral, and autonomic function.
(See a nice review ⬇️ sciencedirect.com/science/articl…)
A critical marker of disability is postural instability🚶➡️🧑‍🦯➡️🧑‍🦽, which leads to falls, and increased morbidity and mortality. The frequency and time-to postural instability in different monogenic parkinsonisms remained unknown.
Read 16 tweets
In this thread, I will compile my medical illustrations in oncology and #RadOnc.

Many are from textbook w @DanTrifMD
amazon.com/Absolute-Clini…
based on @ARRO_org study guide for board exams.

A picture is worth 1000 words.
Here is oncology in a few pics.
@DanTrifMD @ARRO_org @SpringerNature Starting with pediatrics:
Rhabdomyosarcoma treatment paradigm for cancers of head/neck depends on parameningeal vs non-parameningeal location. PM is an unfavorable site, affects stage. #sarcoma #HNCSM
@DanTrifMD @ARRO_org @SpringerNature CNS/brain anatomy from sagittal view.
#BTSM
Chapter from @cgr0105, Sameer Nath, from University of Colorado
Read 49 tweets
When Europe bans something that Africans have mastered (like ganga), our puppet leaders are quick to adopt it & disadvantage us. But when they ban something truly dangerous, like aluminum cooking utensils, our leaders will ignore it, because they really don't GAF about our health
If you have never thought about it, pls do so today.... Where is the other half of that aluminum ladle or spoon??? Unlike the "dad3s3n" which was a cast iron pot (still inferior to the Clay pot, but more later) these aluminum cooking pots are a serious health hazard.
The proof is very simple. Break (so there is no metal contact) fresh kontomire into 3 cooking pots containing water. One clay, one cast iron (or stainless steel) and one aluminum pot. Boil for 10 mins. Remove samples from each & place on a clean white cloth to inspect ...
Read 8 tweets
PING @UQ_EAIT. This semester I've had the opportunity to tutor '#Biomaterials in Medicine' (CHEE4305) & today was the most fun I've ever had in a class at UQ!

The topic was @elonmusk's revolutionary tech startup #Neuralink, aiming to develop implantable brain devices.
A THREAD!
So what makes Neuralink so revolutionary?

Historic Biomaterial revolutions - pacemakers, hip implants, bionic limbs - have changed what humans are capable of doing. However, Neuralink has the potential to change who we are as a species!

theatlantic.com/health/archive…
How can a Biomaterial change the identity of the human species?? What exactly is Neuralink?

This video from @ColdFusion_TV is the most accurate & succinct summary of Neuralink that I've come across:
Read 13 tweets
The Conservative Party of Canada supports a 3 year prohibition on embryonic stem cell research.

They claim adult stems cells are more promising, so let's look at their claims.

#cdnpoli #elxn43 #NeverScheer #stemcells #research #science
The Ford Government has already cut funding for stem cell research.

"Scientist working on treatment of premature babies calls move 'extremely short-sighted and uninformed'"

cbc.ca/news/canada/to…
What are embryonic stem cells?
"Embryonic stem cells exist only at the earliest stages of embryonic development and are capable of making any cell type in the body."

via @UMich

stemcellresearch.umich.edu/overview/faq.h…
Read 9 tweets
1. This is a very useful thread #MedTwitter because it tracks common reasoning errors that lead doctors to readily accept psychosomatic dx for #MEcfs and other contested conditions like #EhlersDanlos, #mito, #dysautonomia, #LymeDisease, etc.
2. Start with the duty that defines your profession @strauss_matt - to ensure that every patient with a need for med care (medical testing, treatment, or support) receives it when she seeks it from you. Mistaken psychosomatic dx violates that duty in every case where it occurs.
3. No doctor should have to be told to err on the side of medical caution. Your job requires (a) humility about the limits of dx science and (b) historical awareness of immense suffering caused by psychological explanations for #MS #epilepsy #PepticUlcer #Parkinsons #lupus etc.
Read 8 tweets
My journey👉🏼of FDA interfering w/ my treatment 4 #MultipleSclerosis "WHEN NO OPTION IS NOT AN ACCEPTABLE OPTION!" #Ortho #cardiac #COPD #Autism #Parkinsons #Cancer

cellr4.org/article/390
Bloomberg @business interviews Celltex patients about experience w/ FDA shutting down adult #stemcell study we in. #MS #Arthritisw #Parkinsons #COPD #Ortho
bloomberg.com/news/articles/…
When left with no viable medical options, what do you do?👉🏼We reached out to other "No Option Patients" and formed PATIENTS FOR STEM STEMCELLS
#MS #PARKINSONS #Autism #COPD #arthritis #ortho #cancer #cardiac patientsforstemcells.org/home/
Read 13 tweets
1/ If u have played the game the way I have, this clip is not that difficult to break down. Notice Wilson’s right skate before or at the initial point of contact. It is leaving the ice intentionally, which means he thrusts his body into an upward direction, which is towards the
2/ head of Reese. If we look at the left skate during the point of contact, Wilson is rising up onto his toe, as if he is trying to jump, hence the reason he ended up sitting on the dasher of his own bench after the hit. It is clear that Reese sees Wilson coming but that has very
3/ little to do with the fact that Wilson clearly makes contact with the head/jaw of Reese, in direct result of jumping and thrusting his body in an upward motion. Bc of this, we have a human being who may get the right diagnosis of a #concussion yet will he receive the treatment
Read 4 tweets

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