Discover and read the best of Twitter Threads about #antibiotic

Most recents (15)

We know antibiotics in the #environment are a driver for #AMR

One intervention to reduce risk in this sector could be formal regulation to control #antibiotic levels in #manufacturing discharge But how viable are these measures? 🧵/1
Antibiotic supply chains are complex & opaque🕵️ This makes it hard for #policymakers to design and implement effective supply chain regulation that reduces #AMR risk but avoids unintended consequences on medicine affordability and availability /2
A new @Wellcome_AMR report attempts to address these ongoing questions through:
- mapping of antibiotic supply chains 🗺️
- analysing likely supply chain & economic impact of regulatory options 💹
- recommending next steps for supply chain sensitive regulatory approaches 🤝
/3
Read 5 tweets
Last year, our sister biotech company @LUCABiologics announced VIRGO, the first comprehensive reference in the gene catalog of the human vaginal #microbiome spearheaded by Chief Scientist Dr. Jacques Ravel. A thread 🧵
This database of nearly 1 million non-redundant genes reveals significant genomic and functional diversity within the vaginal #ecosystem, challenging the widely-held notion that an optimal vaginal microbiome is dominated by one strain. 🧵
This new view of intraspecies diversity has deep implications on the development of gene-centric, microbial therapies to target #diseases like bacterial vaginosis, urinary tract infection, and STI, which impact millions of women globally.🧵
Read 6 tweets
Daily Bookmarks to GAVNet 01/20/2021 greeneracresvaluenetwork.wordpress.com/2021/01/20/dai…
The mathematical case against blaming people for their misfortune | Psyche Ideas

psyche.co/ideas/the-math…

#risk #misfortune #mathematics
Unlocking 'the shape of water' in mechanisms of antibiotic resistance

phys.org/news/2021-01-m…

#shape #antibiotic #resistance #water
Read 8 tweets
Researchers all over the world are looking to identify alternative treatments to reduce antibiotics usage. One such approach taken by @KaushikLab is to evaluate traditional medicinal remedies using modern day scientific tests. bit.ly/2UT5NKs
In this study, they collaborated with an Ayurveda practitioner to identify remedies in ancient Indian texts for wound infections. They found 3 plant-based remedies used for wounds in ancient texts.
Using the plant parts and recipe described, they made these remedies & tested them with laboratory assays against two bacteria known to cause wound infections. They determined that the remedies inhibit bacterial growth to different extents, depending on the bacterial state.
Read 4 tweets
Antibiotics are commonly prescribed medications in the inpatient and outpatient setting and it's important to recognize #AdverseEvents, including idiosyncratic reactions, such as #encephalopathy.

2/
Antibitiotics associated with #Encephalopathy:
- Beta lactams
- #Cephalosporins (#Cefepime is the most common,
Ceftazidime)
- Imipenem
- #Penicillin procaine
- Fluoroquinolones
- Macrolides (clarithromycin)
- TMP-SMX
- #Metronidazole
- Isoniazid

3/
Read 14 tweets
🇬🇧🚜Today is a crucial day for the future of food & farming in the UK

Amongst other things, Govt. decisions today will affect the

🐔quality of food we import
🚜way our food is produced

We need your help to raise awareness of some amendments which must be made to the #AgriBill
✊🚜💚🌍 There has never been a more joined-up coalition of farming & environmental organisations all calling for the same thing

Despite this, the Govt. has continuously failed to protect British food & farming standards in the #AgriBill / #TradeBills ow.ly/gYqs50ArABf
The implications for farmers?

"As a farmer, it could mean my production is undermined by cheap imports from countries with lower standards than in the UK. For society, it could mean we won't have the ability to buy food from local & sustainable supply chains"@hayneoak #AgriBill
Read 11 tweets
1) We are going to breakdown what these meds are here.

#Coronavirus #2019nCoV #WuhanCoronvirus

The first one.

头孢地尼胶囊
Cefdinir capsule is an antibiotic used to treat pneumonia, otitis media, strep throat, and cellulitis.
Ref: en.wikipedia.org/wiki/Cefdinir
2) 連花清瘟膠囊
Lianhua Qingwen

They have 2 of these boxes. This is a herbal medicine.
Interestingly studies show it to be more effective for treating flu.

#Coronavirus #2019nCoV #WuhanCoronvirus

ncbi.nlm.nih.gov/pubmed/29071849
3) 磷酸奥司他韦 胶囊
Oseltamivirphosphate

#Oseltamivir, sold under the brand name #Tamiflu, is an antiviral medication used to treat and prevent #influenza A and influenza B (flu).

#Coronavirus #2019nCoV #WuhanCoronvirus

Drug Ref: webmd.com/drugs/2/drug-1…
Read 15 tweets
Example of organims driving an “#autoimmune” process 👉 In a mouse model of #myocarditis, this team found that cardiac myosin–reactive TH cells are initially primed by myosin-peptide mimics derived from Bacteroides bacteria in the gut: science.sciencemag.org/content/366/64…
2/ Unlike heathy controls, human #myocarditis patients also showed detectable immune reactivity to both Bacteroides and cardiac myosin antigens...
3/ In the mice, #antibiotic treatment dampened inflammatory responses + prevented lethal #heart disease.
Read 3 tweets
It's #WorldAntibioticAwarenessWeek 💊

Misusing and overusing #antibiotics puts us ALL at risk.

You can play a crucial role in reducing #antibioticresistance: only use antibiotics when they were prescribed by a qualified health professional!
@WHOThailand @WHOSriLanka @WHOIndonesia @WHO @WHOTimorLeste @MoHmv @MoHFW_INDIA @UNinIndia @UN_Nepal @MoHFW_GUJARAT The future of #antibiotics depends on all of us.

Drug-resistance is circulating among humans, animals and the environment. #Antibiotic resistance occurs naturally, but misuse of antibiotics in humans and animals is accelerating the process.

#WorldAntibioticAwarenessWeek 💊
Read 4 tweets
1/1 Team uses range of technologies to study brain, heart, kidney + liver tissue of a patient w/ #Lyme disease who received many antibiotics over 16 yrs 👉 Identify significant pathological changes, including borrelial spirochetal clusters in all organs: mdpi.com/antibiotics/an… ImageImageImageImage
2/2 The aggregates contained a well-established #biofilm marker, alginate, on their surfaces, suggesting they are true biofilm 👉 IHC analysis also showed significant numbers of infiltrating CD3+ T lymphocytes present next to #Borrelia burgdorferi biofilms
3/3 Team concludes 👉 “...we provide several lines of evidence that suggest that B. burgdorferi can persist in the human body, not only in the spirochetal but also in the #antibiotic-resistant biofilm form, even after long-term antibiotic treatment”
Read 4 tweets
What if I told you that #BigTech and #SocialMedia platforms are manipulating you, steering you toward #Health information that they think is right, rather than letting you evaluate content for yourself?

Commentary by @MaryamHenein (Thread 👇) theepochtimes.com/google-censors…
Accredited professionals, meanwhile, who stand for #Health freedom and who criticize Big Anything, are losing posting privileges, getting banned, being buried, finding themselves deranked, and getting digitally assassinated.
Content is literally disappearing from the Internet along with our #Health choices.

It sounds conspiratorial because it is. Independent #Journalists and health experts are blowing the whistle. But it’s become a silent one.
Read 94 tweets
This! The activity of the host #immune response largely determines whether #pathobionts acquired from an #FMT donor might become capable of virulence 👉 So including immune status in the study of FMT outcomes would be extremely informative
IMO immune status should be included in the general study of #antibiotic resistant infection 👉 It’s no coincidence that most “superbug” infections occur in immunocompromised patients, often in hospitals (w/ patients on cocktails of steroids for procedures like organ transplants)
Because extrapolate that trend and consider that the immunosuppressive biologics used to palliate “#autoimmune” disease symptoms are the top selling medications in the world 👉 With top side effects of such drugs being “serious #infection by viruses, fungi or bacteria”(see below) Image
Read 6 tweets
thread

Remarkable @bmj_latest @BMJCaseReports report documenting the extreme lengths a bedbound patient went through to get a diagnosis of #POTS, #MCAS, #SIBO and #tachycardia

read her story here

#MedEd #MedTwitter @MayoClinic
casereports.bmj.com/content/2018/b…
2. After suffering for 16 years, seeing 19 docs with repeated misdiagnosis:

Her cardiologist couldnt diagnose #POTS

Her gastroenterologist couldnt diagnose #SIBO

Her immunologist couldnt diagnose #MCAS

Her neurologist referred her to a #psychiatrist!

casereports.bmj.com/content/2018/b…
3. Patient: the "neurologist was out of ideas and suggested I get a psych evaluation, which I declined"

the patient <referred herself> to @MayoClinic

#SickNotWeak #chronicillness #chronicpain #MedEd #medtwitter

casereports.bmj.com/content/2018/b…
Read 10 tweets
Very interesting! 👉 Team found (in mice) that #fever alters surface proteins (integrins) on #immune cells such as lymphocytes + macrophages ☝️ These changes allow such cells to better travel via #blood vessels to reach sites of infection.
And yet, if you walk into a USA #pharmacy, most medications for flu, colds, inflammation, injuries etc deliberately “knock down” #fever to temporarily palliate symptoms 👉 How do such #medications then impact long-term immunity, pathogen persistence and #microbiome health??
This same trend (medications that treat the #immune response as an “enemy” vs. an “ally”) are also “standard of care” for chronic disease 👉 But as such “#autoimmune”/inflammatory conditions are increasingly tied to #microbiome dysbiosis does that paradigm still make sense??
Read 4 tweets
“Missing #microbes” are a factor in the development of chronic #inflammatory disease 👉 But personally, I’m more concerned about the fact that many aspects of modern living are driving a rise in “missing #immunity” and the consequent survival of “additional persistent #pathogens
Here’s an example 👉 #Formula feeding is often associated w/ increased chronic #disease incidence☝️ Meanwhile, #breast milk has a #microbiome, but is ALSO filled w/ antimicrobial compounds + metabolites that play a key role in the immune’s system’s ability to manage #infection
This team found that interactions b/t neonatal #saliva and #breast milk released #antimicrobial compounds including H202☝️These compounds inhibited growth of a range of human pathogens: nature.com/articles/s4159… ImageImageImage
Read 8 tweets

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