Discover and read the best of Twitter Threads about #imaging

Most recents (20)

I see #NHSEx has published the slides from its @HDR_UK “Data Access & Discovery” event, charmingly subtitled “A Forest Through the TREs” - on YouTube, if you want to listen:



__
*I thought the phrase was “cannot see the forest for the TREs”, but hey...
Let’s take a look:

hdruk.ac.uk/wp-content/upl…

One reason we use the category term #TRE to refer to Trusted Research (or any other use) Environments that meet the #FiveSafes is that everyone wants to call their own TRE something different, so no-one really knows what they mean...
Call yours what you like (e.g. for @ONS it's their Secure Research Service) but if it only does four #Safes, or three Safes - and if it isn’t also #consensual and fully #transparent - then it's not a #trustworthy TRE...
Read 24 tweets
Finally, the #GoldacreReview is published! (During Parliamentary Easter holidays, mid-ping-pong on the #HealthAndCareBill...)

It's 221 pages - each PDF page is a double page spread - so this could be a lo-o-o-ong [Thread].

Here goes...
First point to note, in the Terms of Reference (p5), is that this is about "access to #NHSdata by #researchers, #commissioners, and #innovators" - i.e. #Planning and #CommercialReUse - so it is directly relevant to the operation of millions of people's #NationalDataOptOuts... Terms of reference for the review  1. How do we facilitate a
"185 wide-ranging recommendations for us to explore", says @sajidjavid (p6). Gulp! Time for some coffee...

"systems that ensure #underrepresented groups are well represented" may (partly) refer to this "landmark review", which got off to a slow start:

gov.uk/government/new… The far-reaching independent review into potential ethnic bi
Read 159 tweets
The DISCHARGE trial in online on the NEJM and it confirms what we all experience every day using CCT in a proper manner. CCT is safer, reliable and allows better management of stable patients with suspected obstructive CAD as compared to invasive strategy.
The main observation that comes to my mind however is still the very low prevalence of patients with obstructive CAD (25%) in both arms (CT and ICA). This is well known from previous studies and it is related to the selection criteria adopted for referral, partly.
The fact that still we send for an invasive and costly examination (CAG/ICA) this huge number of patients is simply astonishing in 2022. Healthcare cannot be managed like this, especially in universal systems like Italy, Germany, UK, Canada,...
Read 13 tweets
#WeekendLecture
#HistoryofEVT

It’s no secret that #EVT for AIS has been a complete game changer for the field resulting in dramatic reduction in death & disability

Join us to explore the #history of EVT in collaboration with @SVINJournal, to celebrate the inaugural issue Image
Many thanks to @Mahmoudneuro, #RaulNogueira and @DiogoHaussen whose review entitled:
👉“Tx Advancements in the Endovascular Management of Stroke” celebrates the advances in #ETV

🆓 #openaccess

ahajournals.org/doi/full/10.11…
1st #Fun fact: Interventional treatment of AIS dates all the way back to 1950s‼️
Sussman & Fitch reported 3 cases of IA infusion of fibrinolytics
Didn’t work 😫. Probably because they were performed in a non-hyperacute fashion
But this laid the foundation for years of refinement Image
Read 21 tweets
🚨 Interested in single-molecule imaging approaches and/or pore forming proteins? Check out this awesome work from Conall, James and Till at UNSW. Buckle up... 🧵

#UNSW @SingMolSci @Mol_Machines #SingleMolecule #imaging @PratoPores @_DrCJM_ @m_dunstone

doi.org/10.1101/2021.1…
Hold up... if you haven't already done so - follow @Mol_Machines to keep up to date with their awesome single-molecule studies :)
In essence, the study uses #TIRF microscopy to extract #kinetic information, from movies like the one below, for the entire assembly pathway of the pore-forming protein, PFO. What might look like the night sky disappearing, is actually hundreds of independent pore-forming events.
Read 21 tweets
#WeekendLecture
Intracranial Atherosclerotic Disease #ICAD

#ICAD leads to changes ranging from minor wall thickening to #hemodynamically significant luminal stenosis and is one of the most #common causes of #stroke worldwide
ahajournals.org/doi/10.1161/CI…

🧵 Image
#WeekendLecture
#ICAD

✅10% of stroke, based on autopsy studies
bit.ly/3v6Lhrd
✅More prevalent in #African Americans, #Hispanics, and #Asians as compared with whites
bit.ly/3AuSiDt

Other risk factors in table Image
#WeekendLecture
#ICAD

In postmortem studies
👉degree of luminal #stenosis
👉% of the plaques containing >40% #lipid area
👉prevalence of intraplaque #hemorrhage, #neovasculature and #thrombus,
were higher in those #plaques associated with #infarct
🔹karger.com/Article/Abstra… Image
Read 13 tweets
Hi! we are @InafOact and we're happy to join the #CataniaResearchShow. We'll present the latest results of our projects.
Follow the whole show, we'll then pass the baton to @lottabiolab next!
#SharperNight #EuropeanResearchersNight #ERN21 #MSCANight #ERNItaly #SharperNightCatania
#SolarPhysics These images show the latest Hα and continuum image of the Sun acquired at @InafOact with a quality index equal to 1 (1 =good, 3 = bad). They provide a view of the solar chromosphere and photosphere. The observations are carried out between 8:00 and 14:00 CET/CEST.

Unpacking #Juice, the world's first mission to orbit an icy moon. @ESA_JUICE
On board of the payload will be #JANUS, an optical Italian-led camera to study the largest Jupiter moons: #Ganymede, #Callisto and #Europa.
Read 32 tweets
In the #biotech #stocks #NGS field, there is a company that's recently IPOed and has now presented an update of their plans: $OMIC Singular Genomics @SingularGenomi1 investor.singulargenomics.com/static-files/0…
Their two planned instruments, the G4 and the PX, look physically a lot like competitors to the #Illumina NextSeq and NovaSeq, or the #MGI #DNBSEQ G400 and T7 instruments. But the PX is more of a multi-omics play rather than a higher throughput #NGS machine.
It seems we are about 1 year or 1.5 years away from Early Access / Commercial Launch for the PX, maybe around 6 months earlier for the G4 instrument.
Read 9 tweets
(Thread 1/n) The Future of Health & #Medicine: Where Can Technology Take Us?

@daniel_kraft eloquently summarizes the early innings of #healthcare #technology, and its #future. #mustwatch
$XBI $IBB

My favorite takeaways below:

(Thread 2/n) The Future of Health & Medicine:
Where Can Technology Take Us?

Some companies discussed: $TDOC $DRIO $GDRX $AMZN $UBER $AAPL $FIT $AMWL $GOOGL
$GRMN $DXCM $TNDM

@TeladocHealth (I think) would be wise to purchase
@DetectTest @VitalConnectInc @TytoCare @HeartFlow ImageImageImageImage
(Thread 3/n) The Future of Health & Medicine
Glucose Monitoring paving the path forward.

Diabetes care started the path forward. Wearable monitoring, is still in it's infancy. What other applications will come?

@dexcom
@TandemDiabetes
@DarioHealth
@TeladocHealth @Livongo ImageImageImageImage
Read 22 tweets
Daily Bookmarks to GAVNet 04/10/2021 greeneracresvaluenetwork.wordpress.com/2021/04/10/dai…
Complexity Economics: Proceedings of the Santa Fe Institute's 2019 Fall Symposium (Dialogues of the Applied Complexity Network)

jasss.soc.surrey.ac.uk/24/2/reviews/3…

#ComplexityEconomics #SantaFeInstitute #proceedings #book
Read 10 tweets
1/4
43yr chronic #alcohol user on Liv.52 #Herbal supplement for 1yr. Believes Liv52='hepatoprotective'. Consumes along with to cancel alcohol-toxicity. Diabetes uncontrolled on #Ayurveda. Comes with #jaundice, severe #headache, eyes 'bulged' 2 days, nasal discharge #livertwitter Image
2/4
At admission, #seizures, uncontrolled, put on #ventilator. Deep jaundice, comatose. Investigations=acute on #chronic liver failure #aclf
#MRI Brain Part 1👇
Extensive hemorrhagic infarcts, almost all of anterior and mid #brain.
#medicine #MedTwitter #radiology Image
3/4
MRI Brain Part 2👇
Both sides cortical venous thrombosis and anterior third of superior saggitsl sinus thrombus.
#imaging #stroke #NeuroTwitter #neurology #NeuroTwitterNetwork Image
Read 5 tweets
Daily Bookmarks to GAVNet 08/06/2020 greeneracresvaluenetwork.wordpress.com/2020/08/06/dai…
SIAM: A Life of Logic and the Illogic of Life

archive.siam.org/news/news.php?…

#life #logic #tarski
Afraid of Airlines? There’s Always the Private Jet - The New York Times

nytimes.com/2020/07/30/tra…

#jet
Read 10 tweets
Daily Bookmarks to GAVNet 6/21/2020-2

greeneracresvaluenetwork.wordpress.com/2020/06/21/dai…

We're losing the war against surveillance capitalism because we let Big Tech frame the debate

salon.com/2020/06/20/wer…

#capitalism #surveillance #tech
New revelation may change everything we know about coronavirus antibodies

bgr.com/2020/06/20/cor…

#serological #ImmuneSystem #coronavirus
Globalists Reveal That The "Great Economic Reset" Is Coming In 2021

alt-market.com/index.php/arti…

#globalism #EconomicReset
Read 5 tweets
Interested in doing/analyzing #neuroimaging studies in #infants or young #children? New pre-print by @GaabLab led by the wonderful @TedTuresky:
#Neuroimaging the rapidly developing #brain: Current challenges for #MRI studies in the first five years of life
osf.io/7q4cm/
Rapid and widespread changes in #brain anatomy and physiology in the first five years of life present substantial challenges for developmental #MRI studies. One persistent challenge is that methods best suited to earlier developmental stages are suboptimal for later stages
This new review describes the data acquisition, processing, & analysis challenges that introduce these potential biases when conducting & analyzing data from infants and young children & attempts to elucidate decisions & recommendations that can optimize developmental comparisons
Read 4 tweets
Great to have our work on bacterial attachment in stent-on-chips published in @micromach_mdpi at mdpi.com/2072-666X/11/4…!
👇summary thread below👇

With @GarethLuTheryn @aliizzzzz94 @AMosayyebi @Center4Biofilm @MiNaTherGroup @uos_bioengsci @ukbiofilms @UoSEngineering 1/7
Obstructions of the ureter can be caused by a number of factors and affect the physiological flow of urine from kidney to bladder. To overcome this issue, ureteral stents which have side-holes bypassing urine from ureter to stent and viceversa, are clinically implanted. 2/7 Image
However, stents are prone to complications leading to infection. We employed microfluidics to mimic flow dynamics in ureteral stents in different obstruction (obs) conditions: 1) unobstructed 2) obs at proximal side-hole 3) obs in between side-holes 4) obs next to side-hole. 3/7 Image
Read 9 tweets
We are very excited to share our SHANEL method making the intact human organs transparent, just published at Cell. cell.com/cell/fulltext/… by @shan_heather et al.
See short tweetorial for details:
#clearing #imaging #3D #deeplearning #AI @CellCellPress
Mapping the human brain or other organs is a crucial step forward deciphering how they function in health and disease.
Tissue Clearing methods work well on rodent tissue but haven been poorer on stiff & aged human organs. Making the whole human organs transparent required a new approach.
Read 13 tweets
Meet our President, A/Prof Christoph Hagemeyer, @cehagemeyer.

As a #nanotechnology expert and #protein #biochemist, his expertise spans across #stroke therapies, improving diagnostic #imaging and targeted #drug #delivery

A thread 👇

@MonashUni @NanobiotechLab Image
The #2 cause of death worldwide is stroke. Most strokes happen when a blood clot forms and blocks a blood vessel in the brain. Doctors currently use specific therapies that dissolve the clot, allowing blood flow to be returned to the brain, and hopefully, allowing recovery
However, such therapies are associated with severe, sometimes life-threatening adverse bleeding complications. Christoph’s research uses nanotechnology to improve how well this medicine works, while reducing the risk of any side effects.
Read 8 tweets
Hypertrophic Obstructive Cardiomyopathy #HOCM🚧

#Symptoms
Profound exertional dyspnea

#Imaging
▪️SAM/LVOT obstruction #whyCMR
▪️Classic #Doppler🗡#echofirst

#Hemodynamics
▪️Brockenbrough-Braunwald-Morrow sign, explained

#Treatment
▪️Alcohol🍷septal ablation #RadialFirst
Question:
Why wouldn’t more filling time⏱ prior to post PVC beat lead to less obstruction, less gradient, & ↑ arterial pressure?

After all, doesn’t ↑LV volume in #HCM ↓gradient and improve symptoms?

Cornerstone tx is hydration/💊s that ↑ diastolic filling time ...
Read 6 tweets
So excited that the paper that is the culmination of my #PhD came out in @ScienceTM today! As the COVER story! Can't wait to share this 6-yr labor of love with the world. Here are some of the main takeaways from the paper:

#BigDay #HealthTech #PortableMRI #HydrationSensor
MRI is a powerful diagnostic tool but it is too expensive ($1.5M) and time-consuming (10-60min) to use on a regular basis. We developed a portable NMR sensor that can harness the diagnostic power of quantitative MRI at a fraction of the time (<1min) and cost ($1k).
It is not necessary to generate images in order to take quantitative magnetic resonance (relaxometry) measurements. Removing the need to generates images makes the hardware simpler, smaller, and cheaper.

I wrote about this for the @MIT_alumni blog: alum.mit.edu/slice/grad-lif…
Read 16 tweets

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